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Did you know not all Vitamin B6 is alike ? Benefits of the enzymatic form of Vitamin B6 
control homocysteine levels for cardiovascular health
control premenstrual syndrome symptoms
support protein metabolism and muscle growth
support neurotransmitter production for emotional balanceHow can True B6TM help ? 
When the Hungarian scientist, Gyorgy, confirmed the existence of vitamin
B6 in 1934, he knew that it had at least one important function: it
healed an intractable skin disease called acrodynia. Although it took
four more years for German scientists to define the chemical structure
of vitamin B6, nearly every year since then has been marked by the
discovery of disease conditions that improve with vitamin B6, from skin
disease to PMS to cardiovascular disease to porphyria.Sadly, as with so many nutrients, economics rather than health benefits have controlled the quality and availability of vitamin B6 in the marketplace. Notwithstanding the fact that vitamin B6 is an essential nutrient, few know that the true, active form of vitamin B6 is not the inexpensive pyridoxine hydrochloride typically found in vitamin supplements. There are actually three basic forms of vitamin B6 found in the diet, but the fact is that all three, after traveling through the intestinal wall and into the liver, must be converted to the active form of vitamin B6, called pyridoxal 5-phosphate, or P5P, the only form your cells can use. Do we need the active form of vitamin B6 ?
We all know that a healthy body can tolerate foods and perform chemical
reactions that a less-healthy body sometimes cannot. In the case of
inexpensive pyridoxine hydrochloride, your body must have healthy liver
function in order to make the conversion to P5P. Under optimal
conditions, then, P5P is transported through your bloodstream by albumin
to the rest of your cells. Your cells must have P5P, not pyridoxine
hydrochloride, to thrive.This process may not take place, though, if you are suffering from common infections, such as candidiasis. The conversion to P5P in your liver requires a simple chemical reaction called phosphorylation. Unfortunately, during times of infection, phosphorylation slows down, and P5P levels diminish. Your bodyÕs cells may begin to starve for vitamin B6 if nothing but pyridoxine hydrochloride is circulating in your blood. The problem does not end there. Your condition may be further complicated by the pyridoxine hydrochloride that does not convert to P5P. This circulating pyridoxine hydrochloride may actually interfere with vitamin B6 utilization by binding with P5P receptors on cells and preventing true vitamin B6 from entering your cells. Thus, contrary to our instincts, a vitamin B6 deficiency may actually be aggravated by taking the ordinary vitamin B6 found in supplements, pyridoxine hydrochloride. What are some recent discoveries regarding vitamin B6 ?
Although excess cholesterol is still considered a risk factor for
cardiovascular disease, recent research has shifted much of the
attention to homocysteine levels as a far more accurate predictor.
Studies have consistently found a link between cardiovascular disease
and red-meat consumption in Western cultures, but only now is it
becoming clear that homocysteine is one of the key culprits.
Homocysteine is found in much higher levels in the blood of Western
cultures precisely because red meat is high in the amino acid,
methionine, and it is from methionine that homocysteine is made. It is
your body's natural breakdown of homocysteine that is facilitated by
P5P.The fact that enzymatic vitamin B6 can forestall clot formation and the potential for myocardial infarctions (MIÕs) was demonstrated by an analysis of 84 patients with acute myocardial infarction and 84 controls. Subjects with the lowest amount of plasma vitamin B6 were five times more likely to have a myocardial infarction than those with the highest amounts. .......................................................................................................................................... |
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Under optimal conditions, homocysteine is only a transitory amino acid that has no biological value and is quickly converted to cysteine before much damage can be done. The transition to cysteine is important because cysteine plays a role in the formation of collagen and keratin (the proteins found in skin, hair, nails, and connective tissue). Cysteine can further be converted to Taurine, which is the most abundant free amino acid in heart muscle and plays a vital role in regulating the electrical activity of both the heart and brain. It should be clear that if proper levels of P5P are not available, not only will homocysteine begin to accumulate, but the downstream amino acids, cysteine and taurine, may come into short supply. | |||||||||||||
Is there a connection between vitamin B6 and cancer ?
How low levels of vitamin B6 affect cancer and tumor growth is not yet
clear, but new research involving 373 smokers found that those with the
highest folate and vitamin B6 levels had half the risk of contracting
pancreatic cancer as those with the lowest levels. The researchers
concluded that 26% of the pancreatic cancer cases in their study could
potentially have been prevented if the subjects with the lowest vitamin
B6 levels had increased B6 prior to contracting the disease.Although we continue to learn of new health benefits of vitamin B6, it is now clear that the true, enzymatic form of vitamin B6 is the only form to provide those benefits. Recommended Supplementation As a dietary supplement, take one lozenge per
day or as directed by a healthcare professional. |
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